Detroit Lions
| Player | Position | Injury | Wednesday* | Thursday | Friday | Game Status |
|---|---|---|---|---|---|---|
| Brian Branch | DB | ankle | NP | NP | NP | out |
| Jason Cabinda | FB | knee | NP | NP | NP | out |
| James Mitchell | TE | hamstring | not listed | not listed | NP | doubtful |
| Amon-Ra St. Brown | WR | abdomen | NP | NP | NP | doubtful |
| Taylor Decker | T | ankle | LP | LP | FP | questionable |
| Jahmyr Gibbs | RB | hamstring | not listed | not listed | LP | questionable |
| Kerby Joseph | S | hip | LP | LP | FP | questionable |
| Emmanuel Moseley | CB | knee/hamstring | LP | LP | FP | questionable |
| Julian Okwara | LB | shoulder | LP | LP | FP | questionable |
| Josh Reynolds | WR | groin | LP | LP | FP | questionable |
| Halapoulivaati Vaitai | G | knee | LP | LP | FP | questionable |
| Jameson Williams | WR | not injury related** | FP | FP | FP | questionable |
| Frank Ragnow | C | toe/resting player | NP | FP | NP |
*The Lions did not practice on Wednesday. Practice participation designations for that day are based on estimations.
**Return from suspension
