| Player | Position | Injury | Wednesday* | Thursday | Friday | Game status |
|---|---|---|---|---|---|---|
| Christian Izien | DB | Groin | LP | |||
| Derrick Moore | EDGE | Hamstring | LP | |||
| Mekhi Wingo | DL | Groin | LP | |||
| Keith Abney II | CB | Hand | FP | |||
| Thomas Harper | S | Ankle | FP | |||
| Trevor Nowaske | LB | Knee | FP | |||
| Ennis Rakestraw Jr. | CB | Ankle | FP | |||
| Jimmy Rolder | LB | Hamstring | FP |
*The Lions did not practice Wednesday. Practice participation designations for that day are based on estimations.
