| 2021-11-01 | Williams on confidence and faith in Dan Campbell |
| 2021-11-01 | Jefferson on first NFL touchdown |
| 2021-11-01 | Jackson on watching film and improving |
| 2021-11-02 | DLC 2021 Performance Spotlight |
| 2021-11-02 | Lions celebrate 2021 Homecoming |
| 2021-11-03 | Lions surprise Moe Pearson with Salute to Service award nomination |
| 2021-11-03 | Salute to Service 2021 recap |
| 2021-11-04 | Under the Helmet: Anthony Pittman |
| 2021-11-08 | Campbell on keys for remainder of season |
| 2021-11-08 | St. Brown on role in offense moving forward |
| 2021-11-09 | Cheer Spotlight: Carly H |
| 2021-11-10 | DeLeone on progression in linebacker room |
| 2021-11-10 | Lions at Steelers | Week 10 preview |
| 2021-11-10 | Goff on feeling refreshed after bye week |
| 2021-11-11 | Veteran's Day 2021 | Lions Honor Karen Oruwariye |
| 2021-11-11 | Top 10 Lions plays at midway point of 2021 season |
| 2021-11-11 | Lynn on new faces around offense |
| 2021-11-11 | Staley on depth of running back position |
| 2021-11-11 | Fipp on coaching virtually |
| 2021-11-11 | Glenn on the benefits of bye week |
| 2021-11-11 | Reynolds on opportunity to play with Lions |
| 2021-11-11 | Hockenson on finding space downfield |
| 2021-11-11 | Reeves-Maybin on challenges of facing Steelers in Week 10 |
| 2021-11-11 | The X Factor: Week 10 vs Pittsburgh |
| 2021-11-12 | Campbell on executing game plan in Week 10 |
| 2021-11-12 | The Sideline Presented by Kroger | Week 10 |
| 2021-11-12 | Barnes on excitement for Week 10 matchup |
| 2021-11-12 | Jacobs on influence from veteran players |
| 2021-11-13 | 3 and Out with Pittsburgh Steelers Missi Matthews | Week 10 |
| 2021-11-14 | HIGHLIGHT: Okwara records first career INT |
| 2021-11-14 | HIGHLIGHT: Swift activates hurdle at perfect moment on 21-yard run |
| 2021-11-14 | HIGHLIGHT: Igwebuike makes defenders miss on way to 42-yard TD |
| 2021-11-14 | HIGHLIGHT: Goff pinpoints St. Brown in stride for 30-yard gain |
| 2021-11-14 | Campbell on collaborating on the field |
| 2021-11-14 | Swift on finding ways to close out close games |
| 2021-11-14 | Sewell on grinding through hard fought battle |
| 2021-11-15 | Decker on first game back from injury |
| 2021-11-16 | Top 5 plays from Week 10 Next Gen Stats |
| 2021-11-16 | Cheer Spotlight: Valerie |
| 2021-11-17 | Campbell on staying focused on each game |
| 2021-11-17 | Fraley on offensive line performances |
| 2021-11-17 | Lions at Browns | Week 11 preview |
| 2021-11-17 | Goff on status of his injury |
| 2021-11-17 | Harris on affecting the quarterback |
| 2021-11-17 | Sights and Sounds: Week 10 vs Pittsburgh |
| 2021-11-17 | Women in Football Ep. 9 | Jessica Gray |
| 2021-11-18 | Fipp on new kickers |
| 2021-11-18 | Glenn on winning one-on-one scenarios in games |
| 2021-11-18 | Lynn on relinquishing play calling duties |
| 2021-11-18 | Staley on riding hot hand in run game |
| 2021-11-18 | Williams on feeling happy to be back on the field |
| 2021-11-18 | Brockers on playing for his kids and family |
| 2021-11-19 | The X Factor: Week 11 vs Cleveland |
| 2021-11-19 | The Sideline Presented by Kroger | Week 11 |
| 2021-11-19 | Campbell on Week 11 quarterback availability |
| 2021-11-19 | Boyle on opportunity to start in Week 11 |
| 2021-11-19 | Oruwariye on necessity of young players being ready now |
| 2021-11-20 | Lions vs Browns: Week 11 Game Trailer |
| 2021-11-21 | HIGHLIGHT: Oruwariye picks off Mayfield's deep pass attempt |
| 2021-11-21 | HIGHLIGHT: Swift takes off for 57-yard TD run |
| 2021-11-21 | Swift on increased workloads |
| 2021-11-21 | Campbell on Lions playing their hearts out |
| 2021-11-21 | Boyle on first NFL start |
| 2021-11-21 | Oruwariye on defensive mentality |
| 2021-11-22 | Campbell on effort and commitment |
| 2021-11-22 | Cabinda on utilizing his skillset |
| 2021-11-23 | Cheer Spotlight: Dianne |
| 2021-11-23 | The Sideline Presented by Kroger | Week 12 |
| 2021-11-23 | 3 and Out with Tim Twentyman | Week 12 |
| 2021-11-23 | Goff on eagerness to get back on the field |
| 2021-11-23 | Boyle on quick turnaround between games |
| 2021-11-23 | Harris on no quit in locker room |
| 2021-11-23 | Jacobs on tackling as a team |
| 2021-11-23 | Sights and Sounds: Week 11 vs Cleveland |
| 2021-11-24 | Under the Helmet: David Blough |
| 2021-11-24 | Lions vs. Bears | Week 12 preview |
| 2021-11-24 | The X Factor: Week 12 vs Chicago |
| 2021-11-24 | Lions vs Bears: Week 12 Game Trailer |
| 2021-11-25 | HIGHLIGHT: Reynolds makes beautiful toe touch catch for 16 yards |
| 2021-11-25 | HIGHLIGHT: Goff heaves pass to Reynolds for 39-yard TD |
| 2021-11-25 | HIGHLIGHT: Igwebuike does not want to be tackled on 36-yard kickoff return |
| 2021-11-25 | HIGHLIGHT: Oruwariye undercuts Dalton's pass to make phenomenal fingertip INT |
| 2021-11-25 | HIGHLIGHT: Anzalone bottles up Montgomery on third-and-short |
| 2021-11-25 | HIGHLIGHT: Hockenson receives a dart from Goff for 17-yard TD |
| 2021-11-25 | HIGHLIGHT: Onwuzurike swallows up Dalton for first career sack |
| 2021-11-25 | HIGHLIGHT: Williams darts straight through Bears' defense for 19 yards |
| 2021-11-25 | Goff on not making excuses |
| 2021-11-25 | Campbell on miscommunication on field |
| 2021-11-25 | Anzalone on communication and experience |
| 2021-11-29 | Kalif Raymond on My Cause My Cleats |
| 2021-11-29 | Campbell on ignoring critics |
| 2021-11-29 | Hockenson on getting on the same page offensively |
| 2021-11-29 | Onwuzurike on importance of practice |
