| Player | Position | Injury | Wednesday* | Thursday | Friday | Game Status |
|---|---|---|---|---|---|---|
| Michael Brockers | DE | knee/illness | NP | |||
| Jared Goff | QB | illness | NP | |||
| Jonah Jackson | G | illness | NP | |||
| Julian Okwara | OLB | ankle | NP | |||
| John Penisini | NT | illness | NP | |||
| Jalen Reeves-Maybin | LB | shoulder | NP | |||
| D'Andre Swift | RB | shoulder | NP | |||
| Halapoulivaati Vaitai | G | illness | NP | |||
| Nick Williams | DE | illness | NP | |||
| Austin Bryant | OLB | shoulder | LP | |||
| T.J. Hockenson | TE | hand | LP | |||
| Matt Nelson | T | ankle | LP | |||
| Bobby Price | CB | shoulder | LP | |||
| Penei Sewell | T | shoulder/illness | LP |
*The Lions conducted a walkthrough on Wednesday. Practice participation designations for that day are based on estimations.
