Detroit will begin with Pittsburgh this Saturday before Denver, Cleveland and Buffalo.
Watch highlights from the Lions' final preseason game of the 2015 campaign against the Buffalo Bills.
Running back Zach Zenner busts into the end zone for a 3-yard touchdown.
Can't miss play: Wide receiver TJ Jones takes it 64-yards for a touchdown.
Defensive tackle Kerry Hyder recovers his third fumble of the night.
Kellen Moore connects with TJ Jones for a 16-yard reception.