The Lions will be without a number of key starters in the preseason finale in Buffalo tonight.
Running back Reggie Bush and receiver Calvin Johnson are both getting the night off. Johnson has been dealing with a bruised knee over the last few weeks and hasn't played in the preseason since the opener vs. the Jets.
It simply appears to be a night off for Bush, who's carried the ball 17 times for 21 yards and has caught 10 passes for 147 yards in three games.
Receiver Ryan Broyles, running back Montell Owens and tight end Michael Williams will also sit out for the offensive side of the ball.
Receivers Nate Burleson and Patrick Edwards could get some extended work with Johnson and Broyles out. Burleson has just one catch for six yards in the preseason.
"I think it's important this 11 days or whatever it is between then and the first game, you'd like to have at least a little bit of play time," head coach Jim Schwartz said this week.
"We'll take them all by case-by-case basis. Certain guys will play a little bit more than others. I don't think you'll see everybody coming out at the same time. We'll just do the best we can with it."
On defense, both starting safeties Louis Delmas and Glover Quin will sit. Delmas played 16 snaps last week in his preseason debut, but the Lions have been very careful through training camp not to overdue it with that sore left knee.
Tyrell Johnson and Don Carey will start at free and strong safety, respectively.
Quin left last week's game in New England with a hip injury, but has practiced all week and Thursday's decision is just precautionary.
Starting defensive tackle Ndamukong Suh and defensive end Ziggy Ansah are also not playing. Suh has been limited in practice since the New England game with an undisclosed injury, but did get a nice workout in on the field before the game.
Safety John Wendling is also out.
Punter Sam Martin is not among the list of inactive players, despite missing practice time this week with a back injury. Kicker David Akers is expected to handle the kickoff duties, though.